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Publications and funding

 

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Manuscripts

1. J.M. Schober, N. Chen, T.M. Greszkiewicz, I. Jovanovic, E.E. Emeson, T.P. Ugarova, R.D. Ye, L.F. Lau, S.C.-T. Lam. Identification of Integrin aMb2 as an Adhesion Receptor on Peripheral Blood Monocytes for Cyr61 (CCN1) and Connective Tissue Growth Factor (CCN2): Immediate-early Gene Products Expressed in Atherosclerotic Lesions. Blood. 2002;99:4457-4465. Pubmed

 

2. J.M. Schober, L.F. Lau, T.P. Ugarova and Stephen S.C.-T. Lam. Identification of a Novel Integrin aMb2 Binding Site in CCN1 (CYR61), a Matricellular Protein Expressed in Healing Wounds and Atherosclerotic Lesions. Journal of Biological Chemistry. 2003;278:25808-25815. Pubmed

 

3. J.M. Schober, S.C-T. Lam, J.D. Wencel-Drake. Effect of Cellular and Receptor Activation on the Extent of Integrin aIIbb3 Internalization. Journal of Thrombosis and Haemostasis, 2003;1:2404-2410. Pubmed

 

4. G.W. Gant Luxton, J. Lee, S. Haverlock-Moyns, J.M. Schober and G. A. Smith. The Psuedorabies Virus VP1/2 Tegument Protein Is Required for Intracellular Capsid Transport.  Journal of Virology, 2006;80:201-209. Pubmed

 

5. J.M. Schober, Y. Komarova, O. Chaga, A. Akhmanova and G. G. Borisy.  Microtubule-Targeting-Dependent Reorganization of Filopodia.  Journal of Cell Science, 2007;120:1235-1244. Pubmed

 

6. Y. Komarova, Christian O. De Groot, Ilya Grigoriev, Susana Montenegro Gouveia, E. Laura Munteanu, J. M. Schober, Srinivas Honnappa, Rubén M. Buey, Casper C. Hoogenraad, Marileen Dogterom, Gary G. Borisy, Michel O. Steinmetz and Anna Akhmanova. Mammalian EB Proteins Control Microtubule Persistent Growth. Journal of Cell Biology, 2009:184:691-706. Pubmed

 

7. J.M. Schober, Jeanine M. Cain, Yulia A. Komarova and Gary G. Borisy. Migration and actin protrusion in melanoma cells are regulated by EB1 protein. Cancer Letters, 2009:284:30-36. Pubmed

 

8.  Ho-Sup Lee,  Yulia  A. Komarova,  Elena S. Nadezhdina,  Rana Anjum,  John  G.  Peloquin,  J. M. Schober, Oana Danciu, Jeffrey van Haren, Niels Galjart, Steven Gygi, Anna Akhmanova and Gary G. Borisy. Phosphorylation Controls Autoinhibition of CLIP-170. Molecular Biology of the Cell, 2010;21:2661-2673. Pubmed

 

9. J. M. Schober, Guim Kwon, Debbie Jayne, Jeanine M. Cain.  The microtubule-associated protein EB1 maintains cell polarity through activation of protein kinase C. Biochemical and Biophysical Research Communications, 12/2011, in press

 

Abstracts

1.  S.C.-T. Lam, J.M. Schober, V.M. Hadkar, T.P. Ugarova, L.F. Lau. CCN Proteins are Novel Ligands of Integrin  aMb2 on Peripheral Blood Monocytes. Molecular Pathology. 2002;56:68.

 

2. Guim Kwon, J.M. Schober, Theresa Weber, Angela Chiu, Phuong Nguyen, Connie Marshall, Michael McDaniel, Andrew Greenberg. Lipid Droplet formation in the Panceratic β-cell is Regulated by mTOR. American Diabetes Association 69th Scientific Sessions, 2009

 

3. Guim Kwon, J. M. Schober, William L. Neumann, Angela Chiu, Theresa Weber, Phuong Nguyen. AcylCoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor blocks ectopic lipid accumulation but does not rescue β-cells from lipotoxicity. American Diabetes Association 70th Scientific Session, 2010

 

4. J. M. Schober. Activation of Rac1 and PKC rescues polarity defects in EB1 knock down cells. American Society for Cell Biology, 2010

 

5. J. M. Cain and J. M. Schober. Effect of PKC activation on cell motility in EB1 knock-down mouse melanoma cells. Illinois State Academy of Sciences (ISAS), 2011

 

6. J. M. Schober and J. M. Cain. Activation of Rac1 and PKC rescues polarity defects in EB1 knock down cells. American Association for Colleges of Pharmacy (AACP), 2011

 

7.  Z. C. Zhu, H. Sui, B. A. Paulson, K. K. Gupta, J. M. Schober, D. R. Kovar, H. V. Goodson. The Microtubule Plus End Tracking Protein EB1 Binds to Actin and Promotes Actin Polymerization. American Society for Cell Biology (ASCB), 2011

 

 

 

Current Funding

1. 2011-2012 American Association for Colleges of Pharmacy (AACP): EB1 Protein: regulator of cell motility and cancer metastasis (PI: J.M. Schober), $9,441

 

2. 2011-2014 National Institutes of Health (NIH) General Medical Sciences. EB1 protein:  regulator of action protrusion and cell motility (PI: J.M. Schober), $214,500

 

3. 2011 New Directions Award at Southern Illinois University Edwardsville (SIUe) (PI: J.M. Schober and M. Kontoyianni). $9,250

 

 

 

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