Southern illinois University Edwardsville

Chin-Chuan Wei, Ph.D.

The full updated list of the publications can be found at ReserachGate
  • Mai, S. Wei, C.-C.@, Gu, L.-S., Tian, F., Arola, D.D., Chen, J.-H., Jiao, Y., Pashley, D.H., Niu, L.N, Tay, F. R. "Extrafibrillar Collagen Demineralization-based Chelate-and-rinse Technique Bridges the Gap between Wet and Dry Dentin Bonding" Acta biomaterialia 57, 435-438, 2017.
  • Wang, Z.Q., Haque, M., Binder, K., Sharma, M. Wei, C.-C.@, Stuehr,D. J. “Engineering Nitric Oxide Synthase Chimeras to Function as NO Deoxygenates” J. Inorg. Biochem. DOI:, 2016.
  • O'Brien C.L. , Hannah, R. B., Wei, C.-C.@ Shabestary, N., DeMeo, C., Eder, D.J "EDTA:Mg2+ Binding Affinities: A Modern Experiment in Thermodynamics for the Physical Chemistry Laboratory" J. Chem. Educ. 92 (9), 1547-1551, 2015.
  • Wei, C.-–C.@ Jensen, D., Boyle, T., O'Brien, L., DeMeo, C., Shabestary, N. Eder, D. J. "Isothermal Titration Calorimetry and Macromolecular Visualization for the Interaction of Lysozyme and its Inhibitors" J. Chem. Educ. 92 (9), 1552-1556, 2015.
  • Zhang, Feng, X., Yue, X., An, Zhou, W., Gao, J., Hu, T.-P., Wei, C.-C."Effective adsorption of phenols using nitrogen-containing porous activated carbon prepared from sunflower plates" Korean J. Chem. Eng. Publication Date (Web): March DOI: 10.1007/s11814-014-0372-0 2015.
  • Jensen, D., Reynolds, N, Yang, Y.-P., Shakya, S.,Wang, Z.-Q., Stuehr, D. J., Wei, C.-C.@ "The Exchanged EF-hands in Calmodulin and Troponin C Chimeras Reduced Ca2+-induced Hydrophobicity and Alters the Interaction with Orai1: A Spectroscopic, Thermodynamic, and Kinetic Study" BMC Biochemistry 16:6 2015.
  • Zhou, W.-X., Hu, T.-P, Gao, J.-F., Chen, X., Ping, W.-G., Wei, C.-C.@, An, F. "Synthesis of high-performance nitrogen-containing porous carbon and adsorption properties towards metal ions" Desalination and Water Treatment, 1-8, 2014.
  • Wei, C.-C.@, Reynolds, N., Palka, C., Wetherell, K, Boyle, T., Yang, Y.-P.,Wang,Z.-Q., Stuehr, D. J. "Characterization of the 1st and 2nd EF-Hands of NADPH Oxidase 5 by Fluorescence, Isothermal Titration Calorimetry, and Circular Dichroism”" Chemistry Central Journal 6:29 2012.
  • Wang Z.-Q, Tejero, j., Wei, C.-C.@,Haque, M, Santolini, J., Fadlalla, M., Biswas, A.,Stuehr, D. J. “"Arg375 that Interacts with the Tetrahydrobiopterin Cofactor Modulates the Catalysis in Inducible Nitric Oxide Synthase" J. Inorg. Biochem. 2011 Nov 23. [Epub ahead of print] 2011
  • Wei, C.-–C.@,Motl, N.@, Levek, K.@, Chen, L.Q @,Yang, Y.-P, Johnson T.@, Hamilton, L.@, and Stuehr, D. J.“ "Conformational States and Kinetics of the Calcium Binding Domain of NADPH Oxidase 5”" Open Biochem. J. 4, 59-67, 2010.
  • Wang Z.-Q,Wei, C.-–C.@,Stuehr, D. J. “How does a valine residue that modulates heme-NO binding kinetics in inducible NO synthase regulate enzyme catalysis?" J. Inorg. Biochem. 104, 349-356, 2010.
  • Guan Z.-W,Haque, M.,Wei, C. -C.@,Garcin E.D.,Getzoff, E. D., Stuehr, D. J. A Conserved Lys842 in the Autoinhibitory Insert of Neuronal Nitric Oxide Synthase Enables the Insert to Antagonize Calmodulin Binding, Increase FMN Shielding, and Suppress Electron Transfer in Neuronal Nitric Oxide Synthase” J. Biol. Chem. 285, 3064-75, 2010
  • Wei, C.-C.@, Wang, Z.-Q., Tejero, J. Yang, Y.-P. Hemann, C., Hille, R., Stuehr, D.J. "Catalytic Reduction of a Tetrahydrobiopterin Radical Within Nitric Oxide Synthase"” J. Biol. Chem. 283, 11734-42,2008
  • Wang Z.-Q, Lawson, R.J., Buddha, M.R., Wei, C. –C.@,Crane, B.R.,Munro, A.W., Stuehr, D. J. “Bacterial flavodoxins support nitric oxide production by bacillus subtilis nitric-oxide synthase J. Biol. Chem., 282, 2196-202. 2007 - Paper of the week
  • Stuehr, D. J., Wei, C.-C., Wang, Z.-Q., Hille, R. "Exploring the Redox Reactions Between Heme and Tetrahydrobiopterin in the Nitric Oxide Synthases” Dalton Transactions 21, 3427-3435 2005.
  • Wang, Z.-Q., Wei, C.-C., Santolini, J, Wang, Q., Stuehr D. J. “A Tryptophan that Modulates Tetrahydrobiopterin-dependent Electron Transfer in Nitric Oxide Synthase Regualtes Enzyme Catalysis by Additional Mechanism” Biochemistry 44, 4676, 2005.
  • Wei, C.-C.. Hemann, C., Hille, R., and Stuehr, D. J.“The Three Nitric Oxide Synthases Differ in their Kinetics of Tetrahydrobiopterin Radical Formation, Heme-Dioxy Reduction, and Arginine Hydroxylation” J. Biol. Chem., 280, 8929-35, 2005.
  • Stuehr, D. J., Santonili, J., Wang, Z-Q., Wei, C.-C., and Adak, S. “Update on Mechanism and Catalytic Regulation in the NO Synthases” J. Biol. Chem. 279, 36167-36170, 2004.
  • Stuehr, D. J., Wei, C.-C., Santolini, J. Wang, Z.-Q., Aouagi, M., Getzoff, E. D. “Radical Reactions of Nitric Oxide Synthases” Free Radicals: Enzymology Signaling and Disease" Biochemical Society Symposia No. 71. 39-49, 2004 .
  • Wang, Z.-Q., Wei, C.-C., Sharma, M. Pant, K., Crane, B.R., Stuehr, D.J. “A Conserved Val to Ile Switch Near the Heme Pocket of Animal and Bacterial Nitric-Oxide Synthase Helps Determine Their Distinct Catalytic Profiles” J. Bilo. Chem. 279, 19018-19025, 2004
  • Wei, C.-C., Wang, Z.-Q, Stuehr, D. J. “What Controls Tetrahydrobiopterin Radical Formation in NO Synthases” Pterins, Folates and Neurotransmitters in Molecular Medicine (edit by Blau, N and Thony, B), SPS Verlagsgesellschaft , 48-55, 2003.
  • Wei, C.-C., Wang, Z. -Q, Hemann, C., Hille, R., and Stuehr, D. J. “A Tetrahydrobiopterin Radical Forms and then Becomes Reduced During Nw-Hydroxy-Arginine Oxidation by Nitric Oxide Synthase” J. Biol. Chem. 278, 46668-46673, 2003.
  • Wei, C.-C., Crane, B. R., and Stuehr D. J. "Tetrahydrobiopterin Radical Enzymology" Chem. Rev. 103, 2365-2383, 2003.
  • Wei, C.-C., Wang, Z.-Q., Arvai, E.D., Hemann, C., Hille, R., Cetzoff, E. D., and Stuehr, D. J. “Structure of Tetrahydrobiopterin Tunes its Electron Transfer to the Heme-dioxyl Intermediate in Nitric Oxide Synthase" Biochemistry 42, 1969-1977, 2003.
  • Wang, Z.-Q, Wei, C.-C, Santolini, J., and Stuehr D. J. “Mutationn of W457 Alters N-hydroxy-L-Arginine Oxidation by Inducible NO Synthase: A Single Turnover Study” Chemistry and Biology of Pteridines and Folates , (edit by Milstien S, Kapatos, G., Levine R. A., and Shane, B), Kluwer Academic Publisher , 133-138, 2002.
  • Wang, Z.-Q., Wei, C.-C., and Stuehr, D. J. “A Conserved Tryptophan (W457) Modulates the Kinetics and Extent of N-Hydroxy-L-Arginine Oxidation by Inducible Nitric Oxide Synthase” J. Biol. Chem. 277, 12830-12837, 2002.
  • Wei, C. -C., Wang, Z.-Q, Meade A., McDonald, J. and Stuehr, D. J. "Why Nitric Oxide Syntheses Use Tetrahydrobiopterin? J. Inorg. Biochem. 91, 618-624, 2002.
  • Wei, C. -C., Wang, Z. -Q., and Stuehr D. J. “Use of stopped-flow Spectroscopy under Single Turnover Conditions to Examine the Formation and Reactions of the Heme-O2 intermediate in Nitric Oxide Synthase catalysis” Methods in Enzymology: Enzyme Kinetics and Mechanism , Part F, Volume 354, Ed. D.L. Purich, Elsevier Science, 2002.
  • Wang, Z., Wei, C. -C., Hemann, C., Hille, R., and Stuehr D. J. “Single Turnover Studies with Inducible Nitric Oxide Synthase Mutants: A Conserved Trytophan Regulates H4Biopterin-dependent Heme-dioxy Reduction During NO Synthesis” Biochemistry , 40, 10819-12825, 2001.
  • Wei, C. -C., Wang, Z., Wang, Q., Meade, A. L., Hemann, C., Hille, R., and Stuehr, D. J. “Rapid Kinetic Studies Link Tetrahydrobiopterin Radical Formation, Heme-dioxyl Reduction, and Arg Hydroxylation in Inducible Nitric Oxide Synthase” J. Biol. Chem. 276, 315-319, 2001.
  • Wei, C. -C. Balasta, M. L., Ren. J. and Goss, D. J. "Wheat Germ Poly(A) Binding Protein (PABP) Enhances the Binding Affinity of Eukaryotic Initiation Factor 4E and (iso)4F for Cap Analogs" Biochemistry 7, 1910-1916, 1998.
  • Le, H., Tanguary, R. L., Balasta, M. L., Wei, C. -C., Browning, K. S., Goss, D. J., and Gallie, D. R. "Translation Initiation Factors eIFiso-4G and eIF-4B Interact with Poly(A)-Binding Protein to Increase Its RNA Binding Activity" J. Biol. Chem. 272, 16247-16255, 1997.
  • Chow, T. J., Wei, C. -C., Wu, T. K., Martin, H. -D., and Mayer, B. "Transannular Interactions in Polycyclic Hydrocarbons" J. Org. Chem. 60, 5651, 1995.
  • Chow, T. J., Wei, C. -C. and Wu, T. K. “ Chemistry Cage-Shaped Hydrocarbons: The Oxidation of Heptacyclotetradecane” J. Chin. Chem. Soc. 41, 833-841, 1994.
  • Wei, C. -C., Yang, Y. -P., and Chow T. J. "Strained Double bonds in Two Types of Polycyclic Hydrocarbons" Tetrahedron 49, 2201, 1993.
  • Wei, C. -C. and Chow, T. J. "Using Lombardo's Regent to Improve the Olefination" Bull. Chem. Acta. Sinica, 39, 7, 1992.