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Experimental Eye Research
Volume 47, Issue 1 , July 1988, Pages 87-96

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doi:10.1016/0014-4835(88)90026-7
Copyright © 1988 Published by Elsevier Science Ltd.

##

The calibre changes of retinal vessels subject to prolonged hyperoxia

S. Hague, D. W. Hill and A. Crabtree

Department of Ophthalmology, Royal College of Surgeons, Lincoln's Inn Fields, London WC2A 3PN, U.K.
Received 4 August 1987; accepted 26 January 1988. ; Available online 28 January 2004.

## Abstract

The constriction of retinal vessels occurring in response to breathing 100% oxygen was studied in 10 normal subjects over a period of 30 min. Brachial blood pressure, radial pulse and end tidal CO2 were recorded throughout. The mean arteriolar constriction was 15·3%±4·6 and venous constriction 21·8%±4·3. Time constants (the time for 95% of the maximal response to have occurred) were 2·25 min±0·75 and 2·37 min±0·57 for arterioles and veins respectively. A highly variable late vascular response was recorded. A small proportion of arterial vessels showing a response were nonuniform while a larger proportion of veins showed a significant dilatation.

Author Keywords: hyperoxia; retina; calibre; image analysis

Corresponding author. To whom correspondence should be addressed.

|  | This Document |  |
|  |  | Abstract |  |
|  | External Links |  |
|  | Actions |  |
|  |  | Cited By |  |
|  |  | Save as Citation Alert |  |
|  |  | E-mail Article |  |
|  |  | Export Citation |  |
Experimental Eye Research Volume 47, Issue 1 , July 1988, Pages 87-96

|  |  |  | 37 of 40 |

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