Syllabus

ENTX 6300 – Molecular and Genetic Toxicology

 

 

 

CLASS

 

Topic

 

Sept 3

Introduction, course organization,

Oxidative stress I

 

Sept 5

Oxidative Stress II

 

Sept 10

Oxidative Stress III

 

Sept 12

DNA Damage I

 

Sept 17

DNA Damage II

 

Sept 22

DNA Repair I

 

Sept 24

DNA Repair II,

 

Sept 29

DNA methylation

 

Oct 1

Cell cycle delay, Perturbations to the Cell Cycle

 

Oct 6

Cell signaling & sensing toxicant stress

 

Oct 8

Perturbations to intra- and intercellular signaling

 

Oct 13

Perturbations to intra- and intercellular signaling

 

Oct 15

Apoptosis

 

Oct 20

Molecular Carcinogenesis

 

Oct 22

Exam

 

Oct 27

Phase I metabolism

 

Oct 29

Phase II Metabolism

 

Nov 3

Receptor-mediated gene activation by xenobiotics

 

Nov 5

Receptor-mediated toxicity

 

Nov 10

No Class, SETAC

 

Nov 12

No Class, SETAC

 

Nov 17

Hormones & retinoids

 

Nov 19

Molecular mechanisms of developmental toxicity

 

Nov 24

Molecular mechanisms of adaptation and resistance to xenobiotics

 

Nov 26

Thanksgiving

 

Dec 1

Molecular mechanisms of adaptation and resistance to xenobiotics

 

Dec 3

Role of transgenic and gene-targeted  organisms in toxicology

 

Dec 8

Inhibition of gene expression

Dec 10

Toxicogenomics and toxicoproteomics