CLASS

Topic

Sept 3

Introduction, course organization,

Oxidative stress I

Sept 5

Oxidative Stress II

Sept 10

Oxidative Stress III

Sept 12

DNA Damage I

Sept 17

DNA Damage II

Sept 22

DNA Repair I

Sept 24

DNA Repair II,

Sept 29

DNA methylation

Oct 1

Cell cycle delay, Perturbations to the Cell Cycle

Oct 6

Cell signaling & sensing toxicant stress

Oct 8

Perturbations to intra- and intercellular signaling

Oct 13

Perturbations to intra- and intercellular signaling

Oct 15

Apoptosis

Oct 20

Molecular Carcinogenesis

Oct 22

Exam

Oct 27

Phase I metabolism

Oct 29

Phase II Metabolism

Nov 3

Receptor-mediated gene activation by xenobiotics

Nov 5

Receptor-mediated toxicity

Nov 10

No Class, SETAC

Nov 12

No Class, SETAC

Nov 17

Hormones & retinoids

Nov 19

Molecular mechanisms of developmental toxicity

Nov 24

Molecular mechanisms of adaptation and resistance to xenobiotics

Nov 26

Thanksgiving

Dec 1

Molecular mechanisms of adaptation and resistance to xenobiotics

Dec 3

Role of transgenic and gene-targeted  organisms in toxicology

Dec 8

Inhibition of gene expression

Dec 10

Toxicogenomics and toxicoproteomics