| Organization Name | Description | Organization Type | Campus Box | Adviser Campus Box Phone Number |
| A Cross Between Campus Ministry | Provides spiritual assistance and encouragement in all areas of life. Open to all students. | Religious | 1168 | Robert LeAnder Box 1801 618-650-2554 |
| Baptist Student Ministries | Purpose is to proclaim the Gospel of Jesus Christ in meeting the needs of the campus community. Open to all students. | Religious | 1168 | Gregory Crook Box 1040 618-650-2190 |
| Campus Crusade for Christ | CCC exists to provide regular opportunities to study and discuss the Bible, worship, and pray, all in a group setting, which also provides opportunities for fellowship, encouragement and spiritual development among members. | Religious | 1168 | Christine Emling |
| Will foster the spiritual, service, and social interests of Catholic students. Open to all students. | Religious | 1059 | Claudia Calzetta |
| Chi Alpha Christian Fellowship | The purpose of this organization shall be to promote the spiritual and social life of the college student of SIUE by providing those opportunities for worship, fellowship, training, and evangelism, which will accomplish those ends. | Religious | 1168 | Darleen Harmon |
| Christian Student Fellowship | Provides an encouraging, enriching fellowship for students united by faith in Christ. Open to all students. | Religious | 1168 | Craig Miner |
| Evangelical Lutheran Church of America (ELCA) | Study Bible from ELCA perspective, outreach to community through volunteerism, enhance spirituality of selves and others. | Religious | 1168 | Kathleen Tunney Box 1450 618-650-5428 |
| God’s Annointed Mime Ministry | God’s Anointed Mime Minstry is created with desire and full intent as chosen vessels to speak through the flow of movement without saying a word. | Religious | 1168 | Rozina Coleman |
| Hillel Foundation | This is a National Jewish Organization. The pupose is to provide a Jewish presence on campus. | Religious | 1168 | Diane Sol |
| Intervarsity Christian Fellowship | To witness Jesus Christ and to deepen spiritual life. Open to all students. | Religious | 1168 | Ryan Krauss |
| Lutheran Campus Ministry | Purpose is to provide an environment in which SIUE students, staff and faculty can come together in fellowship that is practiced by the Lutheran Church Missouri-Synod. | Religious | 1168 | John Savoie |
| Meals and Music Ministries | Purpose of this organization is to make disciples of Jesus Christ at Southern Illinois University Edwardsville through meals, music, Bible study and reflection, fellowship, athletics and good works. | Religious | 1168 | Anthony Denkyirah |
