Biochemistry, Pharmacogenomics
A.B., 1974, Washington University in St. Louis
Ph.D., 1982, Washington University in St. Louis
Postdoctoral, 1982-1984, Washington University in St. Louis & Texas Tech Health
Sciences Center
Research:
Human genetic variation in drug response and adverse reactions
Genomics of human commensal lactic acid bacteria
Please see the personal webpage http://rx-genomics.pharmacy.siue.edu for current research activities and opportunities for students
Representative publications:
Waterston et al., Initial sequencing and comparative analysis of the mouse genome., Nature, 420 (6915), 520-62, 2002
Pharr PN, Hofbauer A, Worthington RE, Longmore GD., Residual erythroid progenitors in W/W mice respond to erythropoietin in the absence of steel factor signals. Int J Hematol. 2000 Aug;72(2):178-85.
Rubinstein, E., Carroll, R.C., Worthington, R.E., and C. Boucheix. Platelet activation by receptors for the Fc domain of IgG. Seminars in Thrombosis and Hemostasis, 21:10-22, 1995.
CD9 antigen is involved with human smooth muscle cell migration. L. C. Engel, C. Boucheix, R. E. Worthington. Blood 82(6):246, 1993 (abstr.).
Miniswine model for antiplatelet antibody-induced thrombocyopenia mediated by Fc receptor activation. R. C. Carroll, J. Tyler, M. H. Goldman, S. Stevens, and R. E.Worthington. International Society on Thrombosis and Haemostasis, 69(6):1027-1033, 1993.
Worthington, R.E., Aubry, J.P. Studies of changes in cytoplasmic pH and membrane potential using flow cytometry. In Flow Cytometry: New Developments, A. Jacquemin-Sablon, ed., Springer-Verlag, Berlin, pp. 17-28, 1993.