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School of Pharmacy
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Associate Professor of Pharmaceutical Sciences
Phone:  618-650-5168
Fax:  618-650-5145
E-mail:  rworthi@siue.edu

Personal webpage:  http://rx-genomics.pharmacy.siue.edu

Ron Worthington


Pharmacogenomics, Pharmaceutical Biotechnology
A.B., 1974, Washington University in St. Louis
Ph.D., 1982, Washington University in St. Louis
Postdoctoral, 1982-1984, Washington University in St. Louis & Texas Tech Health
Sciences Center


Research:

Human genetic variation in drug response and adverse reactions
Antibacterial peptides against lactic acid bacteria

Please see the personal webpage http://rx-genomics.pharmacy.siue.edu for current research activities and opportunities for students

Representative publications:

Carroll, Roger C, Worthington, Ronald E, Craft, Robert M, Snider, Carolyn C, Dakin, Patrick A, Wortham, Dale C, Scott, Jason, Jarrrett, Ashley, Post interventional cardiology urinary thromboxane correlates with PateletMapping detected aspirin resistance. Thromb Res, 2010. 125(4): p. e118-22.

Waterston et al., Initial sequencing and comparative analysis of the mouse genome., Nature, 420 (6915), 520-62, 2002

Pharr PN, Hofbauer A, Worthington RE, Longmore GD., Residual erythroid progenitors in W/W mice respond to erythropoietin in the absence of steel factor signals. Int J Hematol. 2000 Aug;72(2):178-85.

Rubinstein, E., Carroll, R.C., Worthington, R.E., and C. Boucheix. Platelet activation by  receptors for the Fc domain of IgG. Seminars in Thrombosis and Hemostasis, 21:10-22, 1995.

CD9 antigen is involved with human smooth muscle cell migration. L. C. Engel, C. Boucheix, R.  E. Worthington. Blood 82(6):246, 1993 (abstr.).

Miniswine model for antiplatelet antibody-induced thrombocyopenia mediated by Fc receptor  activation.  R. C. Carroll, J. Tyler, M. H. Goldman, S. Stevens, and R. E.Worthington.  International Society on Thrombosis and Haemostasis, 69(6):1027-1033, 1993.

Worthington, R.E., Aubry, J.P. Studies of changes in cytoplasmic pH and membrane potential  using flow cytometry. In Flow Cytometry: New Developments, A. Jacquemin-Sablon, ed.,  Springer-Verlag, Berlin, pp. 17-28, 1993.

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