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Technology Transfer

Graduate Students

Currently Available SIUE Technologies

Title: A Combined-Loop Magnetic Refrigerator
Project Leaders: Serdar Celik, Chris Euler, and Mehmet H. Kural
Unit: Mechanical Engineering (SIUE)
Executive Summary: This invention is related to a magnetic refrigerator where a magnetocaloric material is used which heats up when a magnetic field applied on it and cools down when the magnetic field is removed. In a general reciprocating magnetic refrigerator, a heat transfer fluid which is driven by a circulation pump flows through a heat exchanger-magnetocaloric material assembly and absorbs the heat when the material heats up. Due to space restrictions, heat exchanger designs are limited to compact models. The invention involves a compact and efficient heat exchanger along with a solenoid valve so that a compact magnetic refrigerator is achieved. In this invention, the warm and cold sides of the cycle are combined using a solenoid valve so that the one single loop is shared by both warm and cold fluids. Hence less space is occupied making it feasible for magnetic refrigeration systems to be applied to domestic refrigerators.
Patent Status: US patent application 20120222428 published September 6, 2012.
Contact: Susan Morgan, Associate Dean for Research, (618) 650-2171.
Title:   Methods For Treating Chronic Pain
Project Leaders: Bill Neumann (SIUE), Smita Rausaria (SIUE), and Daniela Salvemini (SLU)
Unit: School of Pharmacy (SIUE)
Executive Summary: One third of Americans suffer from some form of chronic pain, (30% being resistant to analgesic therapy), making it a significant health problem with serious economic impact (estimated cost of approximately $100 billion annually). Chronic pain associated with inflammatory diseases such as rheumatoid arthritis and chronic neuropathic pain is often difficult to treat in the clinic due to insufficient understanding of the nociceptive pathways involved. Current drug regimens are marginally effective and often display unacceptable side effects. Over the past decade, our multidisciplinary team has produced experimental results which clearly implicate the overproduction of peroxynitrite as a key mediator of inflammatory and chronic pain states in addition to the development of morphine-induced hyperalgesia and antinociceptive tolerance. Thus, the direct scavenging of this neurotoxic entity by small molecule drugs which act in enzyme-like catalytic fashion provides an unconventional approach to a completely novel analgesic strategy.
Brief Description: This invention relates to our design and synthesis of new membrane-permeable and orally active transition metal complexes which behave as catalysts for the decomposition and/or reduction of peroxynitrite in vivo.
Patent Status: US patent application 20120135973 published May 31, 2012.
Contact: Susan Morgan, Associate Dean for Research, (618) 650-2171.
Title: Digitial Potentiostat Circuit and System
Project Leaders: Bradley Noble and Micheal Shaw
Unit: Electrical and Computer Engineering; Department of Chemistry (SIUE)
Executive Summary: Research in fuel cell and solar cell technology requires the use of a "potentiostat", i.e. a device which can measure current output at carefully controlled electrical potentials. Our work has been to use inexpensive, programmable PSOC chips to design and demonstrate working models of digital potentiostats. Inexpensive yet high-quality potentiostats would benefit both research and education applications: hands-on experience with real electrochemical systems from the high-school through college level would lead to a generation with fundamental understanding of how energy-producing cells work.
Patent Status: US patent #8,845,870, issued September 30, 2014. Click title link above to view patent.
Contact: Susan Morgan, Associate Dean for Research, (618) 650-2171.
Title: Bacteriocin/Bacteriophage Derived Methods to Control Lactic Acid Bacterial Growth
Project Leader: Ron Worthington
Unit: School of Pharmacy
Executive Summary: The invention relates to compositions and methods for protection against bacterial contamination.
Patent Status: Two US patents issued - Click title link above for more information and links to patents.
Contact: Susan Morgan, Associate Dean for Research, (618) 650-2171.
Title: Phase-preserving amplifier for a stellar interferometer
Project Leader: Jack Glassman
Unit: College of Arts and Sciences - Department of Physics
Executive Summary: The invention embodies a means of amplifying the signals collected by telescopes while retaining their phase in order to increase the efficiency of these systems, allowing large systems to collect better data faster or allowing systems too small to be useful without amplification to collect useful data.
Patent Status: US patent 7,154,608, issued December 26, 2006. Click title link above to view patent.
Contact: Susan Morgan, Associate Dean for Research, (618) 650-2171.
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